产品编号：F371030

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	F371030
名称:	Flavokawain C
别名:	(E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; 2',4-Dihydroxy-4',6'-dimethoxy-trans-chalcone; 4-Hydroxyflavokawain B; Flavokavin C
CAS号:	37308-75-1
分子式:	C₁₇H₁₆O₅
分子量:	300.31
种类:	Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
应用:	Flavokawain Cis achalcone found in the kava plant. Studies showed thatFlavokawain C can inhibit cell cycle and promote apoptosis in HCT 116 cells. In addition, natural chalcones have beenimplicated as lead compounds for developing dual inhibitors againstHistone deacetylase enzymes (HDACs) and NF-κB. Flavokawain C is a related compound Flavokawain A (F371020).
参考文献	Orlikova, B., et al.: Oncology Reports 28, 787 (2012); Phang, C., et al.: Plos One. 11, e0148775/1 (2016); Juvale, K., et al.: Bioorg. Med. Chem. 20, 346 (2012); Liu, Z., et al.:Cancer Prev. Res 6, 1365 (2013)