产品编号：F371020

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	F371020
名称:	Flavokawain A
别名:	(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; 4-Methoxyflavokawain B; Flavokavin A
CAS号:	37951-13-6
分子式:	C₁₈H₁₈O₅
分子量:	314.33
种类:	Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
应用:	Flavokawain A is achalcone found in the kava plant. It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway. Furthermore, natural chalcones have beenimplicated as lead compounds for developing dual inhibitors againsthistone deacetylase enzymes (HDACs)and NF-κB.
参考文献	Orlikova, B., et al.: Oncology Reports 28, 787 (2012); Juvale, K., et al.: Bioorg. Med. Chem. 20, 346 (2012); Liu, Z., et al.:Cancer Prev. Res 6, 1365 (2013)