产品编号：E926113

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	E926113
名称:	2-​(4-​Ethylphenyl)​-​2-​methylpropanoic Acid
别名:	4-Ethyl-α,α-dimethylbenzeneacetic Acid
CAS号:	1247119-83-0
分子式:	C₁₂H₁₆O₂
分子量:	192.25
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-​(4-​Ethylphenyl)​-​2-​methylpropanoic Acid an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
参考文献	Kinoshita, K. et al.: J. Med. Chem., 64, 6286 (2011); Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);