产品编号：E588918

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	E588918
名称:	Eplerenone 3-Ethylene Ketal
分子式:	C₂₆H₃₄O₇
分子量:	458.54
溶解度:	Dichloromethane; Ether; Ethyl Acetate
种类:	Building Blocks; Miscellaneous;
应用:	Eplerenone 3-Ethylene Ketal is an product intermediate in synthesizing 6β,21-Dihydroxy-Eplerenone (E588750). Eplerenone (E588775) is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987); Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001); Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004); Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005)