产品编号:E102500
产品规格:5mg
产品价格:面议
| 标准品编号: | E102500 |
| 名称: | E 7449 |
| 别名: | 8-[(1,3-Dihydro-2H-isoindol-2-yl)methyl]-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one; |
| CAS号: | 1140964-99-3 |
| 分子式: | C₁₈H₁₅N₅O |
| 分子量: | 317.34 |
| 种类: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | E 7449 is a dual inhibitor of PARP1/2 and tankyrase1/2 exhibits anti-tumor activity in BRCVIP(LA)deficient in vivo models. PARP1/2 and tankyrase1/2 are involved with DNA damage and canonical Wnt/β-catenin signaling, respectively. |
| 参考文献 | |