产品编号：D473860

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D473860
名称:	(3R,4R)-4-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-2-azetidinone
参考CAS号:	Enantiomer: 1620998-81-3
分子式:	C₃₀H₃₃F₂NO₃Si
外观:	白色固体
分子量:	521.67
溶解性:	DCM, Ethyl Acetate
种类:	Standards; Miscellaneous;
应用:	(3R,4R)-4-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-2-azetidinone is an intermediate in the synthesis of (3’R,3R,4R)-Ezetimibe (E974990), a structural analog of Ezetimibe (E975000). Ezetimibe is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.
参考文献	van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)