产品编号：D473390

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	D473390
名称:	(αR,δS,γR)-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-hydroxy-α-(phenylmethyl)benzenehexanoic Acid
别名:	[αR-(αR*,γR*,δS*)]-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-hydroxy-α-(phenylmethyl)benzenehexanoic Acid; (αR,γR,δS)-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-hydroxy-α-(phenylmethyl)benzenehexanoic Acid
CAS号:	98818-43-0
分子式:	C₂₄H₃₁NO₅
分子量:	413.51
溶解性:	DCM, Ethyl Acetate
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αR,δS,γR)-δ-[[(1,1-Dimethylethoxy)carbonyl]amino]-γ-hydroxy-α-(phenylmethyl)benzenehexanoic Acid is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD).
参考文献	Dias, L. C., et al.: Synthesis., 4, 603 (2003); Evans, B.E., et al.: J. Org. Chem., 50, 4615 (1985);