产品编号：D460327

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D460327
名称:	N-(2,3-Dimethoxybenzyl)homopiperonylamine-d6
别名:	N-[(2,3-Dimethoxyphenyl)methyl]-1,3-benzodioxole-5-ethanamine-d6
参考CAS号:	未标记：264625-29-8
分子式:	C₁₈H₁₅D₆NO₄
外观:	Yellow Oil
分子量:	321.4
溶解性:	DCM
种类:	Building Blocks; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
应用:	N-(2,3-Dimethoxybenzyl)homopiperonylamine-d6 is a useful synthetic intermediate in the synthesis of Berberine Hydrochloride-d6 (B318152); the isotope labelled analog of Berberine Hydrochloride (B318150) which is an isoquinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
参考文献	Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999)