产品编号：D454920

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D454920
名称:	(2S,3R,11bS)-Dihydrotetrabenazine
CAS号:	8862377-33-1
分子式:	C₁₉H₂₉NO₃
分子量:	319.44
种类:	Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2S,3R,11bS)-Dihydrotetrabenazine is an enantiomer of (2R,3S,11bR)-Dihydrotetrabenazine (D454925). Tetrabenazineand dihydrotetrabenazines are potent inhibitors ofvesicular monoamine transporter 2(VMAT2). Furthermore, the derivatives of these compounds are potential drug candidates for treating various diseases such asHuntington’s disease and other hyperkinetic disorders.
参考文献	Yao, Z., et al.:ÂEur. J. Med. Chem. 46, 1841 (2011); Duffield, A. J. and Williams, N. A.ÂPCT Int. Appl. WOÂ2010026434ÂA1Â20100311(2010); Grayson, B. et al.:ÂPCT Int. Appl. WOÂ2009150474ÂA1Â20091217 (2009); Nichols, P. P.ÂBrit. UK Pat. Appl. GBÂ2463451ÂAÂ20100317 (2010)