产品编号:D452830
产品规格:25g
产品价格:面议
| 标准品编号: | D452830 |
| 名称: | 7,8-Dihydroxyflavone |
| 别名: | 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one; 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one; |
| CAS号: | 38183-03-8 |
| 分子式: | C₁₅H₁₀O₄ |
| 外观: | Yellow Solid |
| 熔点: | 245-247°C (dec.) |
| 分子量: | 254.24 |
| 储存: | 冰箱保存 |
| 溶解性: | DMSO, Methanol |
| 种类: | Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. It has recently been shown to counteract the inhibition of NMDA receptor caused by lead poisoning and confer protective effects in live rats. |
| 参考文献 | |