产品编号：D450481

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D450481
名称:	(E)-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)acetonitrile
CAS号:	178676-65-8
分子式:	C₁₃H₁₃NO
外观:	白色固体
分子量:	199.25
种类:	Building Blocks; Miscellaneous;
应用:	(E)-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)acetonitrile is an intermediate used in the synthesis of (E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide(Agomelatine Impurity) (D450485), which is an impurity of Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors and used in the treatment of major depressive disorder. Agomelatine Impurity 2
参考文献	Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),