产品编号：D446980

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D446980
名称:	(7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride
别名:	Ivabradine Impurity
CAS号:	1204612-29-2
参考CAS号:	Free Base:1132667-04-9
分子式:	C₁₂H₁₈ClNO₂
分子量:	243.73
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(7R)-3,4-Dimethoxy-N-methyl-bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine is an impurity of Ivabradine (I940500) which is used as a medication for angina and is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node.
参考文献	Mou, S., et al.: Normal phase high performance liquid chromatography (HPLC) method for rapidly analyzing and separating ivabradine hydrochloride intermediate and its optical isomer, China Patent 101609071, Dec 23, 2009; Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),