产品编号：D437025

产品规格：

产品价格：面议

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产品详情

标准品编号:	D437025
名称:	(2R,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol 4-(4-Methylbenzenesulfonate)
CAS号:	1610851-15-4
分子式:	C₂₁H₂₀Cl₂N₂O₅S
分子量:	483.36
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2R,4R)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol 4-(4-Methylbenzenesulfonate) is an impurity of Ketoconazole (K186000), which is antifungal. Ketoconazole is an inhibitor of cytochrome P-450, 5-lipoxygenase and thromboxane synthase.
参考文献	Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)