产品编号：D288740

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	D288740
名称:	N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride
别名:	11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride; DBTP; Norquetiapine; Quetiapine EP Impurity B;
杂质:	Quetiapine EP Impurity B
CAS号:	111974-74-4
参考CAS号:	Free Base: 5747-48-8
分子式:	C₁₇H₁₉Cl₂N₃S
外观:	白色至淡黄色固体
熔点:	>268°C (dec.)
分子量:	368.32
储存:	-20°C Freezer
溶解性:	DMSO, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride (Quetiapine EP Impurity B) is a metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
参考文献	DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001), Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2004), Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2004), Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2006),

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