产品编号：D228592

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D228592
名称:	Defluoro-MDV 3100-d3 (Defluoro-enzalutamide-d3)
别名:	4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-N-methylbenzamide-d3; 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide-d3;
参考CAS号:	未标记：915087-16-0
分子式:	C₂₁H₁₄D₃F₃N₄O₂S
分子量:	449.46
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Defluoro-MDV 3100-d3 (Defluoro-enzalutamide-d3) is the deuterated version of Defluoro-MDV 3100 (Defluoro-enzalutamide) (D228590), which is an impurity of Enzalutamide (M199800) antiandrogen that has been shown to induce tumor cell apoptosis, used to treat castration-resistant prostate cancer.
参考文献	Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011); Ma, X., et al.: J. Pharm. Biomed. Anal., 131, 436 (2016);