产品编号：C989817

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C989817
名称:	β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile-d8
别名:	3-Cyclopentyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propanenitrile-d8
参考CAS号:	未标记：1153949-38-2
分子式:	C₁₇H₁₈D₈BN₃O₂
外观:	白色固体
分子量:	323.27
储存:	冰箱保存, under inert atmosphere
溶解性:	DCM, Methanol
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	β-Cyclopentyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-propanenitrile-d8 is an intermediate in the synthesis of Ruxolitinib (R701995), a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
参考文献	Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);