产品编号：C982468
产品规格：2.5mg
产品价格：面议
| 标准品编号: | C982468 |
| 名称: | CB 1158 |
| 别名: | INCB 01158; α-Amino-α-(4-boronobutyl)-1-[(2,4-dichlorophenyl)methyl]-4-piperidineacetic Acid |
| CAS号: | 1345810-21-0 |
| 分子式: | C₁₈H₂₇BCl₂N₂O₄ |
| 分子量: | 417.13 |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | CB 1158 is a potent arginase inhibitor. CB-1158 has the potential for anti-tumor activity in renal cell cancer, breast cancer, non-small cell lung cancer, acute myeloid leukemia, and other tumor types where arginase-secreting MDSCs are known to play an immunosuppressive role. CB-1158 may also have the ability to combine with other immuno-oncology therapies that target T-cell activation, such as CTLVIP(LA)4 and PD-1 antibodies. |
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