产品编号：C640030

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C640030
名称:	Colchicine Methanethiosulfonate
CAS号:	1217821-52-7
分子式:	C₂₄H₂₉NO₈S₂
外观:	Pale Yellow to 淡黄色固体
熔点:	119-120°C
分子量:	523.62
储存:	-20ËšC Freezer
溶解度:	Chloroform (Slightly), Methanol (Slightly)l
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Sulfhydryl Active Reagents; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	The methanethiosulfonate derfivative of Colchicine (C640000), an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
危险品信息:	Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),

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