产品编号：C181050

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C181050
名称:	4-Carboxy Nevirapine
别名:	11-Cyclopropyl-6,11-dihydro-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepine-4-carboxylic Acid
CAS号:	245501-02-4
分子式:	C₁₅H₁₂N₄O₃
分子量:	296.28
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Benzodiazepines;
应用:	4-Carboxy Nevirapine is a metabolite of Nevirapine (N391275); a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Also antiviral.
参考文献	Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991); Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993); Guay, L.A., et al.: Lancet, 354, 795 (1999); Riska, P., et al.: Drug Metab. Dispos., 27, 895 (1999)