产品编号：B710115

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B710115
名称:	N-Butyldeoxynojirimycin Tribenzoate
别名:	(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triyl Tribenzoate
分子式:	C₃₁H₃₃NO₇
外观:	白色固体
分子量:	531.6
储存:	冰箱保存 (0°C)
溶解度:	Acetone; Chloroform; Dichloromethane; Ethyl Acetate
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Butyldeoxynojirimycin Tribenzoate is an intermediate in the synthesis of Miglustat O-β-D-Glucuronide (M344220), which is a glucuronide derivative of N-Butyldeoxynojirimycin (B691000); an inhibitor of a-glucosidase 1 as well as HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.
参考文献	Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984); Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986); Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988); Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997)