产品编号：B667100

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B667100
名称:	Boc-Saxagliptin
别名:	N-[(1S)-2-[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-Carbamic Acid 1,1-Dimethylethyl Ester;
CAS号:	709031-43-6
分子式:	C₂₃H₃₃N₃O₄
分子量:	415.53
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Boc-Saxagliptin is a Saxagliptin (S143500) impurity, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
参考文献	Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),