产品编号：B591600

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	B591600
名称:	BIX 01294 Trihydrochloride
别名:	2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine Trihydrochloride;
CAS号:	1392399-03-9
参考CAS:	freebase: 935693-62-2
分子式:	C₂₈H₄₁Cl₃N₆O₂
分子量:	600.02
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	BIX 01294 Trihydrochloride is a G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor that H3K9me2 chromatin levels modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in vitro.
参考文献	Kubicek, S. et al.: Mol. Cell., 25, 473 (2007); Huangfu, D et al.: Nat. Biotechnol., 26, 795 (2008); Chang, Y. et al.: Bat. Struct. Mol. Biol., 16, 312 (2009);