产品编号：B448875

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	B448875
名称:	1,1-Bis(p-isobutylphenyl)ethane
别名:	1,1'-Ethylidenebis[4-(2-methylpropyl)-benzene; Ibuprofen Impurity R; Ibuprofen EP Impurity R
杂质:	Ibuprofen EP Impurity R
CAS号:	102120-87-6
分子式:	C₂₂H₃₀
外观:	Clear Colorless Oil
熔点:	未标明外观
分子量:	294.47
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1,1-Bis(p-isobutylphenyl)ethane (Ibuprofen EP Impurity R) is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
文献	Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)

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