产品编号：A621350
产品规格：1mg
产品价格：面议
| 标准品编号: | A621350 |
| 名称: | 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline |
| 别名: | N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine; QNZ; |
| CAS号: | 545380-34-5 |
| 分子式: | C₂₂H₂₀N₄O |
| 状态： | Light Beige to Dark Yellow Solid |
| 熔点： | >170°C (dec.) |
| 分子量: | 356.42 |
| 储存： | 冰箱保存, Under Inert Atmosphere |
| 溶解性: | DMSO (Slightly), Methanol (Slightly, Heated) |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1mg/Kg). A useful tool to explore the role of NFkB in cellular signaling pathways. |
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