产品编号：A601667

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A601667
名称:	N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester-d7
别名:	GS 7485-d7;
备用CAS:	未标记：376633-26-0
分子式:	C₁₅H₁₈D₇N₆O₅P
分子量:	407.41
类别:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Isotope labelled N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
参考:	Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);