产品编号：A112552

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	A112552
名称:	ABT 737-d8
别名:	4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide-d8;
CAS号:	1217686-68-4
备用CAS:	未标记: 852808-04-9
分子式:	C₄₂H₃₇D₈ClN₆O₅S₂
状态：	Yellow Solid
熔点：	148-150˚C
分子量:	821.48
储存：	-20°C Freezer
溶解性:	DMSO
类别:	Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines.
参考:	Ikegaki, N., et al.: Cancer Res., 54, 6 (1994), Kaiser, U., et al.: Lung Cancer, 15, 31 (1996), Rudin, C., et al.: J. Clin. Oncol., 22, 1110 ( 2004), Konopleva, M., et al.: Cancer Cell, 10, 375 (2006), Trudel, S., et al.: Clin. Cancer Res., 13, 621 (2007),