产品编号：A112432

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A112432
名称:	ABT-199-D10
别名:	Venetoclax-d10
备用CAS:	未标记：1257044-40-8
分子式:	C₄₅H₄₀D₁₀ClN₇O₇S
分子量:	878.5
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	ABT-199-D10 is a deuterized form of ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.
参考:	Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);