EL4小鼠淋巴瘤细胞
描述：EL4是从用9,10-二甲基-1,2-苯并蒽在C57BL小鼠中诱导的淋巴瘤中建立的。 能抗0.1 mM 氢化可的松，对20 mcg/ml PHA敏感。 还有一个亚株(EL4.IL-2, ATCC TIB-181)可以生成高水平的IL-2。 检测表明肢骨发育畸形病毒(鼠痘)阴性。
动物种别：小鼠
性别：***
组织来源：T 淋巴细胞；淋巴瘤
培养基和添加剂RPMI-1640(GIBCO,货号31800022, 添加NaHCO3 1.5g/L, glucose 2.5g/L, Sodium Pyruvate 0.11g/L)，90%；马血清，10%。气相：空气，95%；二氧化碳，5%。温度：37摄氏度。。
供应限制：A。仅供研究之用。
REFERENCE：Ralph P . Retention of lymphocyte characteristics by myelomas and theta+-lymphomas: sensitivity to cortisol and phytohemagglutinin. J. Immunol. 110: 1470-1475, 1973. PubMed: 4541304 Old LJ , et al. The G (Gross) leukemia antigen. Cancer Res. 25: 813-819, 1965. PubMed: 4284252 Gorer PA . Studies in antibody response of mice to tumour inoculation. Br. J. Cancer 4: 372-379, 1950. PubMed: 14801344 Herberman RB . Serological analysis of cell surface antigens of tumors induced by murine leukemia virus. J. Natl. Cancer Inst. 48: 265-271, 1972. PubMed: 4119883 Ralph P , Nakoinz I . Inhibitory effects of lectins and lymphocyte mitogens on murine lymphomas and myelomas. J. Natl. Cancer Inst. 51: 883-890, 1973. PubMed: 4542714 Shevach EM , et al. Immunoglobulin and theta-bearing murine leukemias and lymphomas. J. Immunol. 108: 1146-1151, 1972. PubMed: 4112916 Aparicio CL , et al. Correction for label leakage in fluorimetric assays of cell adhesion. BioTechniques 23: 1056-1060, 1997. PubMed: 9421636 Cuthbert JA , Lipsky PE . Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism. Cancer Res. 57: 3498-3504, 1997.
中文名称：小鼠淋巴瘤细胞
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