2-Hydroxy-1,4-naphthoquinone-5,6,7,8-d4 is the isotope labelled analog of 2-Hydroxy-1,4-naphthoquinone (Lawsone) (H949535); the active ingredient of Lawsonia inermis (henna) leaves extract. Lawsone has potential antimicrobial activity and can be used for the detection of latent fingermarks on paper surfaces.