2,4-Bis(phenylmethyl)-3-thioxo-1,2,4-thiadiazolidin-5-one; GSK-3ß Inhibitor III
CAS号:
72966-20-2
分子式:
C₁₆H₁₄N₂OS₂
外观:
白色至白色固体
熔点:
104-107°C
分子量:
314.43
储存:
-20°C Freezer
溶解性:
Chloroform, Dichloromethane, Ethyl Acetate
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. An oxothiadiazolidine-3-thione analogue that acts as a non-ATP competitive inhibitor of GSK-3ß ( IC50 =10uM).
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