(2R,4S)-2-(1,1-Dimethylethyl)-4-[(2E)-1-hydroxy-2-methyl-2-butenyl]-4-methyl-1,3-oxathiolan-5-one is a by-product intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).
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