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产品基本信息
产品编号：C984525
产品名称：[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
产品CAS：66845-32-7
规格含量：100mg
产品价格：面议
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产品详细介绍
标准品编号:
C984525
名称:
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN') Diiodoplatinum
别名:
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN,κN']diiodoplatinum; (1R-trans)-1,2-Cyclohexanediamine Platinum Complex; (trans-1R,2R-1,2-Diaminocyclohexane)diiodoplatinum; (trans-R,R-1,2-Diaminocyclohexane)diiodoplatinum; (trans-R,R-Cyclohexane-1,2-diamine)diiodoplatinum; Diiodo(trans-l-1,2-cyclohexanediamine)platinum; NSC 290127; [SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N')diiodoplatinum; USP Oxiplatin Related Compound F;
CAS号:
66845-32-7
分子式:
C₆H₁₄I₂N₂Pt
外观:
淡黄色固体
熔点:
>300°C
分子量:
563.08
储存:
-20°C Freezer
溶解度:
DMSO (Slightly)
类别:
Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-κN,κN')diiodoplatinum is a potential antitumor agent. Impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
参考文献
Kidani, Y. et al.: Biomed. Pharmacther., 43, 261 (1989); Noji, M. et al.: J. Med. Chem., 24, 508 (1981); Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),
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