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Epothilone E
产品基本信息
产品编号:E589010
产品名称:Epothilone E
产品CAS:201049-37-8
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产品价格:面议
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产品详细介绍
标准品编号: E589010
名称: Epothilone E
别名: (1R,3S,7S,10R,11S,12S,16S)-7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; (-)-Epothilone E; (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
CAS号: 201049-37-8
分子式: C₂₆H₃₉NO₇S
分子量: 509.66
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Epothilone E is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.
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