Desmethoxycarbonyl Nintedanib; Nintedanib Impurity E
CAS号:
262366-32-5
分子式:
C₂₉H₃₁N₅O₂
分子量:
481.59
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent.
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