4-tert-Butylsulfonylcalix[4]arene (CAS# 204190-49-8) calixarene used in the preparation of coordination polymers as a support for Au/Ag nanoparticles. 4-tert-Butylsulfonylcalix[4]arene also appears in the syntheis of stimuli-responsive metal-organic supercontainers as synthetic proton receptors.