E-7046_1369489-71-3_E102400

产品基本信息

产品编号：E102400

产品名称：E-7046

产品CAS：1369489-71-3

规格含量：2.5mg

产品价格：面议

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产品详细介绍

标准品编号:	E102400
名称:	E-7046
别名:	4-[(1S)-1-[[[3-(Difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]-1H-pyrazol-4-yl]carbonyl]amino]ethyl]benzoic Acid
CAS号:	1369489-71-3
分子式:	C₂₂H₁₈F₅N₃O₄
分子量:	483.39
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	E-7046 is an orally bioavailable and specific EP4 antagonist and exhibits anti-tumor activity. EP4 antagonists reverse PGE2-induced suppression of TNFα production in human whole blood.
参考文献	Schiffler, M. et al.: Bioorg. Med. Chem. Lett., 25, 3176 (2015);

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