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产品基本信息
产品编号：C641510
产品名称：Colistin A Sulfate Hydrate (~90%)
产品CAS：
规格含量：5mg
产品价格：面议
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产品详细介绍
标准品编号:
C641510
名称:
Colistin A Sulfate Hydrate (~90%)
别名:
Polymixin E1; 1,4,7,10,13,16,19-Heptaazacyclotricosane Cyclic peptide deriv. Sulfate; Colistin IV Sulfate Hydrate ; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10→4)-Peptide Sulfate Hydrate ; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10→4)-Peptide Sulfate Hydrate
参考CAS:
Free Base: 7722-44-3
分子式:
C₅₃H₁₀₀O₁₃N₁₆ •xH₂SO₄ •xH₂O
外观:
白色固体
熔点:
>230°C (dec.)
分子量:
1169.46
储存:
冰箱保存
溶解度:
Water (Slightly)
类别:
Standards; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
应用:
Colistin A Sulfate Hydrate is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.
参考文献
Wallace, S. et al.: J. Pharm. Sci., 102, 1578 (2013); Suzuki, T., et al.: J. Biochem., 54, 25 (1963); Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964); Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000); Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005); Tsubery, H. et al.: Antimicrob. Agents Chemother., 49, 3122 (2005)
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