(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Hemicalcium Salt; p-Hydroxyatorvastatin Hemicalcium Salt
CAS号:
1263176-34-6
参考CAS号:
free acid: 214217-88-6
分子式:
C₆₆H₆₈CaF₂N₄O₁₂
外观:
白色至Light Beige Solid
熔点:
>190°C (dec.)
分子量:
1187.34
储存:
Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
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