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| 产品基本信息 |
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| 产品编号：F657735 |
| 产品名称：FMK |
| 产品CAS：821794-92-7 |
| 规格含量：1mg |
| 产品价格：面议 |
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| 产品详细介绍 |
| 标准品编号: |
F657735 |
| 名称: |
FMK |
| 别名: |
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone; FMK-MEA; Fluoromethylketone-MEA |
| CAS号: |
821794-92-7 |
| 分子式: |
C₁₈H₁₉FN₄O₂ |
| 分子量: |
342.37 |
| 种类: |
Standards; Enzyme Activators and Inhibitors; |
| 应用: |
FMK is a potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-kinase domain activity. Suppresses RSK2 kinase activity in RSK2-expressing HNSCC cell lines. Reduces HNSCC cell invasive ability. Displays no effect on EGF-stimulated phosphorylation of ERK1 or ERK2. |
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