Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Diisopropyl 4,6-Dimethyl-2-(3-nitrophenyl)-1,2-dihydropyridine-3,5-dicarboxylate is an intermediate used in the synthesis of 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (D291310), which can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).
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