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Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt (80%)
产品基本信息
产品编号:D100085
产品名称:Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt (80%)
产品CAS:
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号: D100085
名称: Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt (80%)
别名: N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine β-D-Glucopyranuronosyl Ester Trifluoroacetic Acid Salt;
参考CAS号: Free Base:1015167-40-4
分子式: C₃₁H₃₃N₇O₉ •xC₂HF₃O₂
外观: 灰白色至浅褐色固体
熔点: >155°C (dec.)
分子量: 647.6411402
储存: Hygroscopic, -20ËšC Freezer, Under Inert Atmosphere
溶解性: DMSO (Slightly), Methanol (Slightly, Heated)
稳定性: Unstable in solution
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is a major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).
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