Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(E)-4-(((R)-2-((1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((1r,3S,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)amino)-4-oxobut-2-enoic acid is a derivative of Saxagliptin, which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
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