36: PN: WO2005049027 PAGE: 99 claimed sequence-d5; L 458-d5; L 685458-d5; γ-Secretase Inhibitor X-d5;
参考CAS号:
未标记：292632-98-5
分子式:
C₃₉H₄₇D₅N₄O₆
分子量:
677.88
种类:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide-d5, is the labeled analogue of D472995, which is a γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD).
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