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产品基本信息
产品编号：C366147
产品名称：3-(2-Chloroethyl-d4)-2-methyl-9-(phenylmethoxy)-4H-pyrido[1,2-a]pyrimidin-4-one
产品CAS：1184973-69-0
规格含量：2.5mg
产品价格：面议
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产品详细介绍
标准品编号:
C366147
名称:
3-(2-Chloroethyl-d4)-2-methyl-9-(phenylmethoxy)-4H-pyrido[1,2-a]pyrimidin-4-one
别名:
3-(2-Chloroethyl-d4)-2-methyl-9-(phenylmethoxy)-4H-pyrido[1,2-a]pyrimidin-4-one; 9-Benzyloxy-3-(2-chloroethyl-d4)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS号:
1184973-69-0
参考CAS:
未标记: 147687-17-0
分子式:
C₁₈H₁₃D₄ClN₂O₂
外观:
白色固体
分子量:
332.82
溶解度:
Dichloromethane
类别:
Building Blocks; Isotopic Labeled Analogues;
应用:
3-(2-Chloroethyl-d4)-2-methyl-9-(benzyloxy)-4H-pyrido[1,2a]pyrimidin-4-one is an intermediate in the synthesis of 9-Hydroxy Risperidone-d4 (H953352), a deuterated metabolite of Risperidone (R525000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
参考文献
Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996); Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998); Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005)
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