6α-Desfluoro-6α-chloro-21-methanesulfonyloxy Halobetasol Propionate is an intermediate for the synthesis of 6α-Desfluoro-6α-chloro Halobetasol Propionate (D291215), which is an impurity of Halobetasol Propionate (H102300), a dermatologic agent commonly used to treat psoriasis.