Building Blocks; Chiral Molecules; Isotopic Labeled Analogues;
应用:
cis-4-Hydroxy-L-proline-d3 is deuterium labelled cis-4-Hydroxy-L-proline (H952375). Hydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.