Denitro 4-Methoxyphenyl Nimesulide is an intermediate in the synthesis of 4’-Hydroxy Nimesulide (H948560), the main metabolite of Nimesulide (N477500), an antiinflammatory agent which preferentially inhibits COX-2 over COX-1, suppresses chemical-induced carcinogenesis in mice and rats and inhibits LPS-induced TNF-alpha production.
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