6α-Chloro-9α-fluoro-11β,17,21-trihydroxy-16β-methyl-Pregna-1,4-diene-3,20-dione is an intermediate for the synthesis of 6α-Desfluoro-6α-chloro Halobetasol Propionate (D291215), which is an impurity of Halobetasol Propionate (H102300), a dermatologic agent commonly used to treat psoriasis.