Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
1-[4-[[(3R,4R)-1-Acetyl-4-methyl-3-piperidinyl]methylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]ehtanone is an intermediate in the synthesis of Tofacitinib Impurity Z (T528030), which is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3 (Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
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