N-[1-[2-(2,4-Dichlorophenoxy)acetyl]-4-piperidinyl]-4-merc_2060530-16-5_D438295

产品基本信息

产品编号：D438295

产品名称：N-[1-[2-(2,4-Dichlorophenoxy)acetyl]-4-piperidinyl]-4-merc

产品CAS：2060530-16-5

规格含量：10mg

产品价格：面议

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产品详细介绍

标准品编号:	D438295
名称:	N-[1-[2-(2,4-Dichlorophenoxy)acetyl]-4-piperidinyl]-4-mercapto-butanamide
CAS号:	2060530-16-5
分子式:	C₁₇H₂₂Cl₂N₂O₃S
分子量:	405.34
种类:	Standards; Enzyme Activators and Inhibitors;
应用:	N-[1-[2-(2,4-Dichlorophenoxy)acetyl]-4-piperidinyl]-4-mercapto-butanamide is an irreversible and allosteric inhibitor of the K-Ras(G12C) mutant. This compound has potential therapeutic application for diseases related to Ras signaling.
参考文献	Hunter, J. C., et al.: Proc Natl Acad Sci U S A. 111, 8895 (2014); Lim, S. M., et al.: Angew Chem Int Ed Engl. 53, 199 (2014)

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